Tumours of Unknown Origin

ADAMANTINOMA    [Back To Top] 

• An extremely rare, locally aggressive osteolytic low-grade malignant tumour of epithelial origin of the long bones
• It is not related to adamantinoma or ameloblastoma of the mandible and maxilla which is derived from Rathke's pouch.
• Site: tibia (90%)
• Age 10-40 years
• M>F
• 20% of cases there are metastases late in the course of the disease

Presentation

• There is often a history of trauma associated with adamantinoma but its role in the development of this lesion remains unclear
• The patient usually has swelling that may be painful
• The duration of symptoms can vary from a few weeks to years