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Tumours of Unknown Origin

ADAMANTINOMA    [Back To Top] 

  • An extremely rare, locally aggressive osteolytic low-grade malignant tumour of epithelial origin of the long bones
  • It is not related to adamantinoma or ameloblastoma of the mandible and maxilla which is derived from Rathke's pouch.
  • Site: tibia (90%)
  • Age 10-40 years
  • M>F
  • 20% of cases there are metastases late in the course of the disease


  • There is often a history of trauma associated with adamantinoma but its role in the development of this lesion remains unclear
  • The patient usually has swelling that may be painful
  • The duration of symptoms can vary from a few weeks to years

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